سنتز و مشخصه‌یابی نانوذرات مغناطیسی فریت کبالت- روی قرار گرفته شده در پلیمر حساس به دما

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشکده فنی و مهندسی، گروه مهندسی مواد، دانشگاه شهرکرد، شهرکرد، ایران

2 پژوهشکده فناوری نانو و مواد پیشرفته، پژوهشگاه مواد و انرژی، کرج، ایران

چکیده

در این مقاله یک روش ساده و نوین برای ساخت نانوذرات مغناطیسی قرار گرفته در یک پلیمر حساس به دما گزارش شده است. به منظور ساخت نانوذرات مغناطیسی فریت کبالت- روی پایدار از روش سنتز تجزیه حرارتی استفاده شده است. اولئیل آمین که به عنوان سورفکتانت در این روش استفاده می‌شود می‌تواند باعث ایجاد عامل آب‌گریز در سطح نانوذرات گردد. زمانی‌که کوپلیمر حساس به دمای آمفیفیلیک روی سطح نانوذرات قرار می‌گیرد منجر به پایدار‌سازی نانوذرات در محیط آبی می‌گردد. روش پراش اشعه ایکس (XRD) و طیف سنجی مادون قرمز (FTIR) برای بررسی ساختار و تشخیص فاز اسپینل استفاده شدند. اندازه بلورک در نانوذرات مغناطیسی با استفاده از روش ریتولد محاسبه گردید. با استفاده از تصویر TEM اندازه نانوذرات در حدود 1±9 نانومتر تخمین زده شد. دمای LCST پلیمر با استفاده از دستگاه UV-Visible به‌دست آمد و با توجه به نتایج حاصل مشخص گردید که این کامپوزیت پلیمری حاوی نانوذرات مغناطیسی توانایی استفاده در کاربردهای پزشکی از جمله تثبیت پروتئین، درمان سرطان با استفاده از هایپرترمیا و دارورسانی هدفمند را دارد.

کلیدواژه‌ها


عنوان مقاله [English]

Synthesis and Characterization of Co-Zn Ferrite Nanoparticles Embedded in a Thermo-Sensitive Polymer

نویسندگان [English]

  • Ibrahim Sharifi 1
  • Ali Zamanian 2
  • Aliasghar Behnamghader 2
1 Faculty of Engineering, Department of Material Engineering, Shahrekord University, Shahrekord, Iran
2 Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC) , Tehran, Iran
چکیده [English]

This article reports a simple and novel method to synthesize magnetic nanoparticles embedded into thermo-sensitive copolymers. To form a stabilized suspended core, Co-Zn ferrite nanoparticles synthesized through thermal decomposition method. Oleylamine as a surfactant used as hydrophobic agent at the surface of nanoparticles. Amphiphilic thermo-sensitive copolymer linked with magnetic nanoparticles. Composite of magnetic nanoparticles and polymers can be suspended in hydrophobic media. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) used as structural analysis to confirm spinel structure. Crystallite size of magnetic nanoparticles estimated by Rietveld refinement from XRD patterns. The particle diameters measured approximately 9±1 nm with TEM micrograph. Also, UV-visible used as a method to determine LCST temperature of nanoparticles. These novel magnetic thermo-responsive composite have potential applications in biomedical applications, such as, protein immobilization, hyperthermia cancer therapy and target drug delivery systems.
 

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