عنوان مقاله [English]
Recently, composite scaffolds prepared by electrospinning have shown desirable properties for tissue engineering applications. In this study, first the nBGs were prepared via the sol-gel technique, then, the electrospun PHB/nBG nanocomposite scaffolds (with 7.5, 10 and 15 wt% of nBGs) were fabricated. The nanoparticles and scaffolds were characterized by Scanning Electron Microscopy (SEM), X-ray diffraction spectrometer (XRD), X-rayfluorescence spectroscopy (XRF), Fourier transform infrared spectroscopy (FTIR). Results showed that nanoparticles with an amorphous structure mainly had a particle size of less than 70 nm. All the nano-fibrous scaffolds had a uniform distribution of interconnected porosities with fiber diameters ranging from 326.1 nm to 1.276 micrometer. Composite scaffolds having nanoparticle concentrations higher than 7.5 wt%, tend to agglomerate. In addition, the FTIR results showed a favorable interaction between the polymer and nBGs. Therefore, the proposed PHB/nBG scaffolds prepared in this study can be considered as good candidates for bone tissue engineering applications.