Authors
1 Islamic Azad University (Najafabad branch), Esfahan, Iran
2 Isfahan University of Medical Sciences, Esfahan, Iran
Abstract
In this study, firstly hydroxyapatite powder using natural method and bovine bone was synthesized at temperature of 900 ° C. Then it was synthesized reproducibiliby from foam ceramic scaffolds with 0, 3, 6 and 9 wt% and 50 wt% titania hydroxyapatite wet grinding method (slurry). In order to detect the changes of phase and chemical bonds was used diffraction of X-rays and infrared light spectroscopy. Microstructure and morphology of the nano composites was examined by scanning electron microscopy. According to the results, the volume fraction of porosities were obtained about 80-85%. The compressive strength was measured 0.14 to 1.321 MPa .Results indicate that the best type of scaffold physical properties such as porosity and shrinkage after sintering about low percentages of titanium dioxide, the 3 and mechanical properties suitable, the high percentage of titanium dioxide is the 6 percent.
Keywords
- Nhaput, C., Selmani, A., Rivard, C.H., “Artificial scaffolding materials for tissue extracellular matrix repair”, Current Opinion in Orthopaedics, vol. 7(160), p. 62, 1996.
- Gomes, M., “A Bone tissue engineering strategy based on starch scaffolds and bone marrow cells cultured in a flow perfusion bioreactor”, Department of Polymer Engineering, University of Minho, 2004.
- Lanza, R., Langer, R., Vacanti, J., Principle of Tissue Engineering, Academic Press, Third Edition, 2007.
- Jun, I.K., “Porous Hydroxyapatite Scaffolds Coated With BioactiveApatite–Wollastonite Glass–Ceramics”, J. Am. Ceram. Soc., pp. 1-6, 2007.
- M.R, Karbasi.S, Ebrahimi-Kahrizsangi.R, “Physical and mechanical properties of a poly-3-hydroxybutyrate-coated nanocrystalline hydroxyapatite scaffold for bone tissue engineering”, Journal of Porous Materials. 667-67 19(5). 2012.
- Montazeri M, Karbasi. S, Ebrahimi-Kahrizsangi.R, “Physical and mechanical properties of a Poly hydrozibotyrat-Bio-Glass- scaffold for bone tissue engineering”, Journal of Porous Materials.565-77 20(5). 2012.
- A, Foroughi.M.R, Monshi. M.R, “Modified Scherrer Equation to Estimate More Accurately Nano-Crystallite Size Using XRD”, World Journal of Nano Science and Engineering. 1542 (3). 2012.
)