Journal of Advanced Materials and Technologies

Journal of Advanced Materials and Technologies

Chemical Synthesis and Characterization of Physical and Magnetic Properties of Cobalt Doped Hydroxyapatite Nanoparticles

Document Type : Original Reaearch Article

Authors
Narges Yazdani
Jafar Javadpour
Bijan Eftekhari Yekta
Iran University of Science and Technology, school of material and metallurgy, Tehran, Iran
10.30501/jamt.2637.70326
Abstract
 Synthesis of HAp is of considerable interest because of its similariity to mineral component of bone. It has good biocompatibility and bioactivity for bone tissue therapy. In this project, we looked at the effect of calcium substitution with cobalt divalent cation on the structure and magnetic property of HAp. Cobalt- doped HAp  nanoparticles was synthesized via hydrothermal condition. First, Calcium nitrate and Cobalt nitrate was mixed. Then di- ammonium hydrogen phosphate was added drop by drop and finally Co-HAp was precipitated from the solution.  The precipitate was heated at 200°C under hydrothermal condition. XRD pattern analysis verified the substitution of cobalt in HAp structure by showing a shift in the peak positions in the pattern. Furthermore, broadening and reduction in the peak intensities of the peaks with cobalt substitution was also observed in this study. The presence of functional groups
related to HAp structure (PO43-, OH-) were confirmed by FTIR analysis. The size and morphology of nanoparticle HAp
particles were evaluated by FESEM analysis.  Calcium substitution with cobalt induced size reduction and morphology
change in HAp particles. VSM analysis was carried out to investigate the magnetization of HAp and Co-HAp nanoparticles. The results showed that cobalt substituted nanoparticles displayed paramagnetic properties, as opposed to the diamagnetism of pure HAp. Cobalt doped HAp, a biomaterial with magnetic properties, could be used in a variety
of biomedical applications, including magnetic imaging, drug delivery and hyperthermia based cancer treatment.
  
Keywords
Hydroxyapatite
Cobalt Doped Hydroxyapatite
Hydrothermal Condition
Noparticles
Paramagnetic
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Journal of Advanced Materials and Technologies
Volume 5, Issue 2
Summer 2016
Pages 1-8

  • Receive Date 12 July 2015
  • Revise Date 16 August 2016
  • Accept Date 23 August 2016