Journal of Advanced Materials and Technologies

Journal of Advanced Materials and Technologies

Wound Dressings Based on Pectin

Document Type : Research Review Article

Authors
Pegah Poorkhalili 1
Jhamak Nourmohammadi 2
Masoumeh Haghbin Nazarpak 3
1 MSc Student, College of Interdisciplinary Science and Technology, University of Tehran, Iran
2 Associate Professor, College of Interdisciplinary Science and Technology, University of Tehran, Iran
3 Assistant Professor, New Technologies Research Center (NTRC), Amirkabir University of Technology (AUT), Tehran, Iran
10.30501/jamt.2025.484957.1308
Abstract
The wound healing process consists of four stages: hemostasis, inflammation, proliferation, and remodeling. Many wound dressings are designed to enhance the body’s ability to close wounds and restore the function of damaged tissues. Recently, pectin has been utilized for various biomedical applications, including wound healing, due to its simple gel-forming mechanism and cell compatibility. The hydrophilic pectin particles in the dressing interact with wound exudate to form a soft gel layer on the wound bed, effectively absorbing exudates. Additionally, the acidic environment created by the dissolution of pectin may serve as a barrier against bacteria and viruses. This study reviews recent research on pectin for biomedical applications, extending beyond traditional uses in food or pharmaceuticals. It discusses the structure of pectin and extraction methods, focusing on the polysaccharide properties that can optimize gels for specific applications, thereby playing a crucial role in its biomedical use. Various crosslinking methods for pectin structures in medical applications are introduced, along with their respective advantages and disadvantages. The role of electrospun pectin fibers in wound healing applications is also specifically addressed.
Keywords
Wound Dressing
Pectin
Hydrogel
Nanofibers

Subjects

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Journal of Advanced Materials and Technologies
Volume 13, Issue 4
Winter 2025
Pages 40-56

  • Receive Date 18 November 2024
  • Revise Date 24 December 2024
  • Accept Date 03 March 2025