Physical and Mechanical properties of a poly-3-hydroxybutyratecoated namocrystalline bioglass 45S5 scaffold for bone tissue engineering

Montazeri, Mahboobeh; Karbasi, Saeed; Monshi, Ahmad; Ebrahimi- Kahrizsangi, Reza; Foroughi, Mohammad Reza

doi:10.30501/jamt.2013.129376

Physical and Mechanical properties of a poly-3-hydroxybutyratecoated namocrystalline bioglass 45S5 scaffold for bone tissue engineering

Authors

Mahboobeh Montazeri ¹

Saeed Karbasi ²

Ahmad Monshi ³

Reza Ebrahimi- Kahrizsangi ⁴

Mohammad Reza Foroughi ⁴

¹ Islamic Azad University (Najafabad Branch), Esfahan, Iran

² Isfahan University of Medical Science, Esfahan, Iran

³ Isfahan University of Technology, Esfahan, Iran

⁴ Islamic Azad University (Najafabad branch), Esfahan, Iran

10.30501/jamt.2013.129376

Abstract

Because of wide range applications of bioglass in medicine, industrial production of large amount of nano bioglass is very important. In the study firstly, nano-Bioglass (nBG) 45S5 powder was made from industrial materials by heat treatment at temperature of 1400 c. the nanoparticle of biglass with grain size between 55- 65 mm was made by ball- mill method. then porous bioglass scaffolds iwll produce by using of polyurethane sponge replication method. results showed that the porosity of scaffolds in between 75- 87% and the compressive strength is 0.1-0.3 MPa. it is concluded that this scaffold could be a good candidate for bone tissue engineering.

Keywords

Bioglass 45S5. Scaffold

Fusion method

Bone tissue engineering