The as-cast and homogenized microstructures of Al10Co25Cr8Fe15Ni36Ti6 high entropy alloy were investigated in this study. To this end, the high entropy alloy was produced using vacuum induction melting and electro slag remelting processes, and the ESRed block was homogenized at the temperature of 1220 °C for 17 hr. The as-cast, as ESRed and homogenized microstructures were then investigated using optical microscopy, scanning electron microscopy, and X-ray diffraction. On the basis of theoretical measurements, the mixing entropy, atomic size differences, and Valence electron concentration were obtained as 13.05 kJ/mol, 8.8, and 7.97, respectively. These values can predict the formation of a solid solution matrix as the type of BCC + FCC and intermetallic phases. The as-cast microstructure included γ+ γʹ in the dendritic zones and γʹ+ NiAl in the interdendritic areas. After homogenization, the dendritic structures were almost eliminated, and they became discontinuous which is an indication of elements distribution homogenization. NiAl phase was also omitted after the homogenization process.